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KMID : 0352720090330010033
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Journal of Ginseng Research
2009 Volume.33 No. 1 p.33 ~ p.39
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Effect of White and Red Ginseng Extracts on the Immunological Activities in Lymphocytes Isolated from Sasang Constitution Blood Cells
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Choi Jae-Ho
Oh Deog-Hwan
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Abstract
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The effects of white ginseng and red ginseng ethanol extracts on the proliferation, nitric oxide (NO) production and tumor necrosis factor-α (TNF-α) in human B and T lymphocytes isolated from blood cell of sasang constitution were examined in vitro. White ginseng extract known as medicine suitable for soeumin constitution showed the highest immune activities such as proliferation, NO production and TNF-α in soeumin constitution, and followed by taeeumin and soyangin, respectively (P＜0.05). However, there were immunologically insignificant differences among sasang constitution lymphocytes treated by red ginseng ethanol extract. Both white and red ginseng ethanol extracts showed significantly higher immunological activities than LPS-induced sasang constitution lymphocytes on NO production and TNF-α release (P＜0.05). The different immunological activities of white and red ginseng extracts in sasang constitution lymphocytes might be due to the component changes during the processing of ginseng. Thus, the findings of components suitable for all constitutions from red ginseng extract could be applied as a new constitution marker.
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KEYWORD
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Ginseng, lymphocytes, sasang constitution, proliferation, nitric oxide
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